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Anti-Emetic Administration

Protocol number: ALS-001
Description: Anti-emetic administration
Date implemented: August 12, 2003
Last revision date: January 26, 2006
OMD: Dr. Charles Lane
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Reviewed Date/By:
 
 
 
RATIONALE
Nausea and vomiting are common complaints for not only the initial EMS request, but also as a result of motion created by the emergency vehicle during transport.  Vomiting in the Pre-Hospital setting can lead to many complications, such as airway compromise or aspiration.  It is responsive to drug therapy.
 
DRUG
Promethazine Hydrochloride (Phenergan™) is a very effective anti-emetic that can safely be administered pre-hospital.  Drug class is Phenothiazine.  It is an antihistamine (H1 receptor antagonist) that has the following actions: mild anticholinergic activity, antiemetic, potentiation of analgesics.  Onset is rapid with IV administration and duration of effect is for 4-6 hours.
 
INDICATIONS
 
*ONLINE-     Vomiting and/or significant nausea
                        Motion Sickness
                        Medication side effect (e.g. opiate analgesic)
 
*Must receive Online Medical Direction approval prior to administration of anti-emetic.
 
CONTRAINDICATIONS
  • Altered level of consciousness
  • Trauma Patients
  • Children < 2 years old
  • Elderly > 70 years old
  • Physician order not obtained.

 
Protocol number: ALS-001
Description: Anti-emetic administration
Date implemented: August 12, 2003
OMD: Dr. Charles Lane
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POSSIBLE COMPLICATIONS
  • Injection pain, vein irritation, phlebitis
  • Respiratory Depression
  • Allergic reaction
  • Drowsiness/sedation
  • Impairment mental and physical ability
  • Hypotension
  • Hyperexcitability
  • Dystonic reaction
  • Dysrhythmia
 
INTERACTIONS
Caution with MAO Inhibitors, CNS depressants, Anticholinergics, Alcohol.
 
ROUTE
IV, IM (deep)
 
HOW SUPPLIED
25mg/mL
 
ADULT DOSAGE
6.25 mg, 12.5mg, 25mg  
  • IV
  • IM
 
PEDIATRIC DOSAGE
0.25 mg/kg IV, rarely given
 
EQUIPMENT
Promethazine Hydrochloride (Phenergan™) injectable solution
Patent and well flowing IV access
Sterile injectable saline solution
 
PREPARATION/ADMIISTRATION
1)      Draw up calculated dose of Phenergan in syringe.
2)      Dilute in 3 - 5 cc of sterile saline solution.
Administer over 1 minute thru a well flowing IV line.
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